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Book Pages

Publications (2000-2004)


  1. Sun R.W., Yu W.Y., Sun H.Z., Che C.M. (2004) “In vitro inhibition of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase by gold(III) porphyrinsChemBioChem, 5(9), 1293-1298. doi: 10.1002/cbic.200300773.

  2. Sun X., Sun H.Z., Ge R., Richter M., Woodworth R.C., Mason A.B., He Q.Y. (2004) “The low pKa value of iron-binding ligand tyr188 and its implication in iron release and anion binding of human transferrin”  FEBS Letters, 573(1-3), 181-185. doi: 10.1016/j.febslet.2004.07.076.

  3. Li H.Y., Li F., Qian Z.M., Sun H.Z.* (2004) “Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments” European Journal of Biochemistry, 271(10), 1938-1951. doi: 10.1111/j.1432-1033.2004.04104.x.

  4. Sun H.Z.*, Zhang L., Szeto K.Y. (2004) “Bismuth in medicineMetal Ions in Biological System, 41, 333-378. (Featured on the cover of the issue)

  5. Li F., Sun H.Z.* “Dynamic and kinetic aspects of metallodrugs by NMR” in Fluxional Organometallic and Coordination Chemistry (Edited by Gielen M., Willem R., Wrackmeyer B.), John-Wiley & Sons, 163-217, 2004. doi: 10.1002/0470858451.ch5.

  6. Jin L., Szeto K.Y., Zhang L., Du W.H., Sun H.Z.* (2004) “Inhibition of alcohol dehydrogenase by bismuth” Journal of Inorganic Biochemistry, 98(8), 1331-1337. doi: 10.1016/j.jinorgbio.2004.03.016.

  7. Liu C.L., Wang M., Zhang T.L., Sun H.Z. (2004) “DNA hydrolysis promoted by di- and multi-nuclear metal complexesCoordination Chemistry Reviews, 248(1-2), 147-168. doi: 10.1016/j.cct.2003.11.002.


  1. Zheng Q., Yang W.M., Yu W.H., Cai B., Teng X.C., Yi X., Sun H.Z., Zhang M.J., Huang Z.X. (2003) “The effect of EAAEAE insert on property of human metallothionein-3Protein Engineering, 16(12), 865-870. doi: 10.1093/protein/gzg127.

  2. Li W., Jin L., Zhu N.Y., Hou X.M., Deng F., Sun H.Z.* (2003) “Structure of colloidal bismuth subcitrate in dilute HCl:  assembly of dinuclear [Bi(cit)2Bi]2-Journal of the American Chemical Society, 125(41), 12408-12409. doi: 10.1021/ja037019x.

  3. Li H.Y., Li F., Sun H.Z.*, Qian Z.M. (2003) “Membrane-inserted conformation of transmembrane domain4 of divalent metal transporterBiochemical Journal, 372(Pt 3), 757-766. doi: 10.1042/bj20030075.

  4. Yan S.C., Li F., Ding K.Y., Sun H.Z.* (2003) “Reduction of pentavalent antimony and formation of binary and ternary complex with trypanothioneJournal of Biological Inorganic Chemistry, 8(6), 689-697. doi: 10.1007/s00775-003-0468-1.

  5. Sun H.Z.*, Szeto K.Y. (2003) “Binding of bismuth to serum proteins: implication for targets of Bi(III) in blood plasma”. Journal of Inorganic Biochemistry, 94(1-2), 114-120. doi: 10.1016/S0162-0134(02)00649-9.

  6. Che C.-M.*, Sun R.W.Y., Yu W.Y., Ko B.C.B., Zhu N.Y., Sun H.Z.* (2003) “Gold(III) porphyrins as a new class of anticancer drugs: cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cellsChemical Communications, (14), 1718-1719. doi: 10.1039/B303294A.

  7. Lo W.Y., Lam C.H., Fung W.K.M., Sun H.Z., Yam V.W.W., Balcells D., Maseras F., Eisenstein O. (2003) “An oscillating C22- unit inside a copper rectangleChemical Communications, (11), 1260-1261. doi: 10.1039/B301842C.

  8. Yan S.C., Wong L.K., Chow L.M.C., Sun H.Z.* (2003) “Rapid reduction of pentavalent antimony by trypanothione: potential relevance to antimonial activationChemical Communications, (2), 266-267. doi: 10.1039/B210240D.


  1. Du X.L., Zhang T.L., Yuan L., Zhao Y.Y., Li R.C., Wang K., Yan S.C., Zhang L., Sun H.Z. Qian Z.M. (2002) “Complexation of ytterbium to human transferrin and its uptake by K562 cellsEuropean Journal of Biochemistry, 269(24), 6082-6090. doi: 10.1046/j.1432-1033.2002.03326.x.

  2. Sun H.Z.* (2002) “Metallodrugs” in Encyclopedia of Nuclear Magnetic Resonance: Advances in NMR (Ed: Grant, D.M. & Harris R.K., John Wiley & Sons Ltd.), 413-427.

  3. Li H.Y., Sun H.Z., Qian Z.M. (2002) “Drug delivery and targeting: the role of transferrin/transferrin receptor systemTrends in Pharmacological Sciences, 23(5), 206-209. doi: 10.1016/S0165-6147(02)01989-2.

  4. Sun H.Z.*, Zhang L., Szeto K.Y. (2002) “Basis of bismuth antiulcers: biological chemistry and pharmacology”. Chinese Journal of Clinical Pharmacology, 18, 297-301. doi: 10.3969/j.issn.1001-6821.2002.04.015.

  5. Zhang R., Yu W.Y., Sun H.Z., Liu W.S., Che C.M. (2002) “Stereo- and enantioselective alkene epoxidations: a comparative study of D4- and D2-symmetric homochiral trans-dioxoruthenium(VI) porphyrinsChemistry, A European Journal, 8(11), 2495-2507. doi: 10.1002/1521-3765(20020603)8:11<2495::AID-CHEM2495>3.0.CO;2-G.

  6. Qian Z.M., Li H.Y., Sun H.Z., Ho K. (2002) “Targeted drug delivery via the transferrin receptor-mediated endocytosis pathwayPharmacological Reviews, 54(4), 561-587. doi: 10.1124/pr.54.4.561. (Featured on the cover of the issue)


  1. Zhang L., Szeto K.Y., Wong W.B., Sadler P.J., Sun H.Z.* (2001) “Interactions of bismuth with human lactoferrin and recognition of Bi(III)-lactoferrin by intestinal cellsBiochemistry, 40(44), 13281-13287. doi: 10.1021/bi010579t.

  2. Sun H.Z., Li H.Y., Mason A.B., Woodworth R.C., Sadler P.J. (2001) “Competitive binding of bismuth to transferrin and albumin in aqueous solution and blood plasmaJournal of Biological Chemistry, 276(12), 8829-8835. doi: 10.1074/jbc.M004779200.


  1. Sun H.Z.*, Yan S.-C., Cheng W.-S. (2000) “Interaction of antimony tartrate with the tripeptide glutathione: implication for its mode of actionEuropean Journal of Biochemistry, 267(17), 5450-5457. doi: 10.1046/j.1432-1327.2000.01605.x.

  2. Yan S.C., Ding K., Zhang L., Sun H.Z.* (2000) “Complexation of antimony(III) to trypanothioneAngewandte Chemie International Edition, 39(23), 4260-4262. doi: 10.1002/1521-3773(20001201)39:23<4260::AID-ANIE4260>3.0.CO;2-9.

  3. Guo M.L., Sun H.Z., McArdle H. J., Gambling L., Sadler P. J. (2000) “TiIV uptake and release by human serum transferrin and recognition of TiIV-transferrin by cancer cells: understanding the mechanism of the anticancer agent titanocene dichlorideBiochemistry, 39(33), 10023-10033. doi: 10.1021/bi000798z.

  4. Guo M.L., Sun H.Z., Bihari S., Parkinson J.A., Gould R.O., Parsons S., Sadler P.J. (2000) “Stereoselective formation of seven-coordinate titanium(IV) monomer and dimer complexes of ethylenebis(o-hydroxyphenyl)glycineInorganic Chemistry, 39(2), 206-215. ​doi: 10.1021/ic990669a.

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