Book Pages

Publications (2005-2009)

2009

  1. Wu Z.Y., Liu Q., Liang X., Yang X., Wang N.Y., Wang X.H., Sun H.Z., Lu Y., Guo Z.J. (2009) “Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1” Journal of Biological Inorganic Chemistry, 14(8), 1313-1323. doi: 10.1007/s00775-009-0576-7.

  2. Ding Z.C., Teng X.C., Zheng Q., Ni F.Y., Cai B., Wang Y., Zhou G.M., Sun H.Z., Tan X.S., Huang Z.X. (2009) “Important roles of the conserved linker-KKS in human neuronal growth inhibitory factor” BioMetals, 22(5), 817-826. doi: 10.1007/s10534-009-9228-1.

  3. Sun X.S., Ge R.G., Chiu J.F., Sun H.Z.*, He, Q.Y.* (2009) “Iron depletion decreases proliferation and induces apoptosis in a human colonic adenocarcinoma cell line, Caco2” Journal of Inorganic Biochemistry, 103(7), 1074-1081. doi: 10.1016/j.jinorgbio.2009.05.004 .

  4. Xia W., Li H.Y., Sze K.H., Sun H.Z.* (2009) “Structure of a nickel chaperone, HypA from Helicobacter pylori reveals two distinct metal binding sites” Journal of the American Chemical Society, 131(29), 10031-10040. doi: 10.1021/ja900543y.

  5. Sun X.S., Baker H.M., Ge R.G., Sun H.Z., He Q.Y., Baker E.N. (2009) “Crystal structure and metal binding properties of the lipoprotein MtsA, responsible for iron transport in Streptococcus pyogenes” Biochemistry, 48(26), 6168-6190. doi: 10.1021/bi900552c.

  6. Cai B., Ding Z.C., Zhang Q., Ni F.Y., Wang H., Zheng Q., Wang Y., Zhou G.M., Wang K.M., Sun H.Z., Wu H.M., Huang Z.X. (2009) “The structural and biological significance of the EAAEAE insert in the α-domain of the human neuron growth inhibitory factor” FEBS Journal, 276(13), 3547-3558. doi: 10.1111/j.1742-4658.2009.07075.x.

  7. Sun X.S., Tsang C.N., Sun H.Z.* (2009) “Identification and characterization of metallodrugs binding proteins by (metallo)proteomics” Metallomics, 1(1), 25-31. doi: 10.1039/B813121J. (Featured on the cover of the January issue, 2009)                                                                       

  8. He J., Hu P., Wang Y.J., Tong M.-L., Sun H.Z., Mao Z.W.* Ji L.-N. (2008) “Double-strand DNA cleavage by copper complexes of 2,2-dipyridyl with guanidinium/ammonium pendants” Dalton Transactions, (24), 3207-3214. doi: 10.1039/B801549J.

  9. He J., Sun J., Mao Z.W., Ji L.N., Sun H.Z. (2009) “Phosphodiester hydrolysis and specific DNA binding and cleavage promoted by guanidinium-functionalized zinc complexes” Journal of Inorganic Biochemistry, 103(5), 851-858. doi: 10.1016/j.jinorgbio.2009.02.010.

  10. Zhou Y.H., Zhao M., Sun H.Z., Mao Z.W., Ji L.N. (2009) “Effect of cyclodextrin dimers with bipyridyl and biphenyl linking groups on carboxyl ester hydrolysis catalyzed by zinc complex” Journal of Molecular Catalysis A: Chemical, 308 (1-2), 61-67. doi: 10.1016/j.molcata.2009.03.026.

  11. Ge R.G., Sun H.Z. (2009) "Metallomics: An integrated biometal science" Science in China Series B Chemistry, 52(12), 2055-2070. doi: 10.1039/B308213J.

  12. Huang J.D., Sun H.Z., Tanner J.A., Watt R.M. (2009) "Determination of the functions of the putatuve metal-binding domain of the SCV helicase" Hong Kong Medical Journal, 15(Suppl 6), 15-16.

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2008

  1. Zeng Y.B., Zhang D.M., Li H.Y., Sun H.Z.* (2008) “Binding of Ni2+ to a histidine- and glutamine-rich protein, Hpn-like (Hpnl)” Journal of Biological Inorganic Chemistry, 13(7), 1121-1131. doi: 10.1007/s00775-008-0397-0.

  2. Cun S.J., Li H.Y., Ge R.G., Lin M.C.M., Sun H.Z.* (2008) “A histidine- and cysteine-rich metal binding domain at the C-terminus of heat-shock protein A from Helicobacter pylori: implication for nickel homeostasis and bismuth susceptibility” Journal of Biological Chemistry, 283, 15142-15151. doi: 10.1074/jbc.M800591200.

  3. Sun X.S., Ge R.G., Chiu J.F., Zu Y.B., Sun H.Z.*, He Q.-Y.* (2008) “Lipoprotein MtsA of MtsABC in Streptococus progenes primarily binds ferrous ion with bicarbonate as a synergistic anion” FEBS Letter, 582(9), 1351-1354. doi: 10.1016/j.febslet.2008.03.020.

  4. Li H.Y., Gu J.D., Sun H.Z.* (2008) “Structure, topology and assembly of a 32-mer peptide corresponding to the loop 3 and transmembrane domain 4 of divalent metal transporter (DMT1) in membrane-mimetic environments” Journal of Inorganic Biochemistry, 102(5-6), 1257-1266. doi: 10.1016/j.jinorgbio.2007.12.019.

  5. Wang H., Li H.Y., Cai B., Huang Z.X., Sun H.Z.* (2008) “The effect of nitric oxide (NO) on metal release from human metallothionein-3 (MT-3): gradual unfolding of the protein” Journal of Biological Inorganic Chemistry, 13(3), 411-419. doi: 10.1007/s00775-007-0331-x.

  6. Sun X.S., Ge R.G., Chiu J.F., Sun H.Z.*, He Q.Y.* (2008) “Identification of proteins related to nickel homeostasis in Helicobater pylori by immobilized metal affinity chromatography and two-dimensional gel electrophoresis” Metal-Based Drug, 2008, 289490. doi: 10.1155/2008/289490.

  7. Huang J.D., Zheng B.J., Sun H.Z. (2008) “Helicases as antiviral drug targets” Hong Kong Medical Journal, 14 Suppl 4, 36-38.

  8. Ding Z.C., Zheng Q., Cai B., Ni F.Y., Yu W.H., Teng X.C., Gao Y., Liu F., Chen D., Wang Y., Wu H.M., Sun H.Z., Zhang M.J., Tan X.S., Huang Z.X. (2008) “Study on structure-property-reactivity-function relationship of human neuronal growth inhibitory factor (hGIF)” Journal of Inorganic Biochemistry, 102 (11), 1965-1972. doi: 10.1016/j.jinorgbio.2008.07.007.

  9. He J., Hu P., Wang Y.-J., Tong M.-L., Sun H.Z., Mao Z.-W., Ji L.-N. (2008) "Double-strand DNA cleavage by copper complexes of 2,2'-dipyridyl with guanidinium/ammonium pendants" Dalton Transactions, 3207-3214. doi: 10.1039/B801549J.

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2007

  1. Ding Z.C., Zheng Q, Can B., Yu W.H., Teng X.C., Wang Y., Zhou G.M., Wu H.M., Sun H.Z., Zhang M.J., Huang Z.X. (2007) “Effect of α-domain substitution on the structure, property and function of human neuronal growth inhibitory factor” Journal of Biological Inorganic Chemistry, 12(8), 1173-1179. doi: 10.1007/s00775-007-0287-x.

  2. Ge R.G., Sun H.Z.* (2007) “Bioinorganic chemistry of bismuth and antimony: target sites for metallodrugs” Accounts of Chemical Research, 40(4), 267-274. doi: 10.1021/ar600001b.

  3. Li H.Y., Fung K.L., Jin D.Y., Chung S.S.M., Ching Y.P., Ng I.O., Sze K.H., Ko B.C.B.*, Sun H.Z.* (2007) “Solution structures, dynamics and lipid-binding of SAM domain from the deleted in liver cancer 2 (DLC2): a monomeric structure with membrane-binding properties” PROTEINS: Structure, Function, and Bioinformatics, 67(4), 1154-1166. doi: 10.1002/prot.21361.

  4. Ni F.Y., Cai B.,  Ding Z.C., Zheng F., Zhang M.J., Wu H.M., Sun H.Z., Huang Z.X. (2007) “Structural prediction of the β-domain of metallothionein-3 by molecular dynamics simulation” PROTEINS: Structure, Function, and Bioinformatics,  68(1), 255-266. doi: 10.1002/prot.21404.

  5. Wong I.L.K., Chan K.F., Burkett B.A., Zhao Y., Chai Y., Sun H.Z., Chan T.H., Chow L.M.C. (2007) “Flavonoid dimers as bivalent modulators for pentamidine and sodium stiboglucanate resistance in Leishmania” Antimicrobial Agents and Chemotherapy, 51(3), 930-940. doi: 10.1128/AAC.00998-06.

  6. Yang N., Sun H.Z.* (2007) “Biocoordination chemistry of bismuth: recent advances” Coordination Chemistry Reviews, 251(17-20), 2354-2366. doi: 10.1016/j.ccr.2007.03.003.

  7. Yang N., Tanner J.A., Zheng B.J., Watt R.M., He M.L., Lu L.Y., Jiang J.-Q., Shum K.-T., Lin Y.-P., Lin M.C.M., Kung H.F., Sun H.Z.*, Huang J.D.* (2007) “Bismuth complexes inhibit the SARS coronavirus” Angewandte Chemie International Edition 46(34), 6464-6468. doi: 10.1002/anie.200701021.

  8. Yang N., Tanner J.A., Wang Z., Huang J.D., Zheng B.J., Zhu N., Sun H.Z.* (2007) “Inhibition of SARS coronavirus helicase by bismuth complexes” Chemical Communications, (42), 4413-4415. doi: 10.1039/B709515E.

  9. Yang Z., Wang X., Diao H., Zhang J., Li H.Y., Sun H.Z., Guo Z.J. (2007) “Encapsulation of platinum anticancer drugs by apoferritin” Chemical Communications, (33), 3453-3455. doi: 10.1039/B705326F. (Featured on the cover of the issue on September 7, 2007)

  10. Ge R.G., Sun X.S., Gu Q., Watt R.M., Wong B.C.Y., Xia H.H.X., Huang J.D., He Q.Y.*, Sun, H.Z.* (2007) “A proteomic approach for the identification of bismuth-binding proteins in Helicobacter pylori” Journal of Biological Inorganic Chemistry, 12(6), 831-824. doi: 10.1007/s00775-007-0237-7.

  11. Lok C.-N., Ho C.-M., Chen R., He Q.-Y., Yu W.-Y., Sun H.Z., Tam P.K.-H., Chiu J.-F., Che C.M. (2007) “Silver nanoparticles: partial oxidation and antibacterial activities” Journal of Biological Inorganic Chemistry, 12(4), 527-534. doi: 10.1007/s00775-007-0208-z.

  12. Zhou Y.H., Fu H., Zhao W.X., Su C.Y., Sun H.Z., Ji L.N., Mao Z.W. (2007) “An effective metallohydrolase model with supramolecular environment: structures, properties and activities” Chemistry, a European Journal, 13(8), 2402-2409. doi: 10.1002/chem.200601302.

  13. Zhou Y.H., Fu H., Zhao W.X., Chen W.L., Su C.Y., Sun H.Z., Ji L.N., Mao Z.W. (2007) “Synthesis, structure, and activity of supramolecular mimics for the active site and arg141 residue of copper, zinc-superoxide dismutase” Inorganic Chemistry,  46(3), 734-739. doi: 10.1021/ic061541d.

  14. An Y., Lin Y.Y., Wang H., Sun H.Z., Tong M.L., Ji L.N., Mao Z.W. (2007) “Cleavage of double-strand DNA by zinc complexes of dicationic 2,2'-dipyridyl derivatives” Journal of Chemical Society, Dalton Transactions, (12), 1250-1254. doi: 10.1039/B616754C.

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2006

  1. Ding Z.C., Teng X.C., Cai B., Wang H., Zheng Q., Wang Y., Zhou G.M., Zhang M.J., Wu H.M., Sun H.Z., Huang Z.X. (2006) “Mutation at Glu23eliminates the neuron growth inhibitory activity of human metallothionein-3” Biochemical and Biophysical Research Communications, 349(2), 674-682. doi: 10.1016/j.bbrc.2006.08.090.

  2. Ge R.G., Zhang Y., Sun X.S., Watt R.M., He Q.-Y., Huang J.D., Wilcox D.E., Sun H.Z.* (2006) “Thermodynamic and kinetic aspects of metal binding to the histidine-rich protein, Hpn” Journal of the American Chemical Society, 128(35), 11330-11331. doi: 10.1021/ja062589t.

  3. Lok C.-N., Ho C.-M., Chen R., He Q.-Y., Yu W.-Y., Sun H.Z., Tam P.K.-H., Chiu J.-F., Che C.-M. (2006) “Proteomic analysis of the mode of antibacterial action of silver nanoparticles” Journal of Proteome Research, 5(4), 916-924. doi: 10.1021/pr0504079.

  4. Chen R., So M.H., Yang J., Deng F., Che C.-M., Sun H.Z.* (2006) “Fabrication of bismuth subcarbonate nanotube arrays from bismuth citrate” Chemical Communications, (21), 2265-2267. doi: 10.1039/B601764A.

  5. Cai B., Zheng Q., Teng X.C., Chen D., Wang Y., Wang K.Q., Zhou G.M., Xie Y., Zhang M.J., Sun H.Z.*, Huang Z.H. * (2006) “The Role of Thr5 in human neuron growth inhibitory factor” Journal of Biological Inorganic Chemistry, 11(4), 476-482. doi: 10.1007/s00775-006-0097-6.

  6. Xue R., Wang S., Wang C.Y., Zhu T., Li, F., Sun H.Z. “HFIP-induced structures and assembly of the peptides from the transmembrane domain 4 of membrane protein, Nramp1” (2006) Biopolymers, 84(3), 329–339. doi: 10.1002/bip.20478.

  7. Wang H., Zheng Q., Cai B., Li H.Y., Sze K.H., Huang Z.X., Wu H.M., Sun H.Z.* (2006) “Solution structure and dynamics of human metallothionein-3 (MT-3)” FEBS Letters, 580(3), 795-800. doi: 10.1016/j.febslet.2005.12.099.

  8. Zhang L., Mulrooney S.B.,  Leung F.K., Zeng Y.B., Ko B.C.B., Hausinger R.P.*, Sun H.Z.* (2006) “Inhibition of urease by bismuth(III): implications for the mechanism of action of bismuth drugs” BioMetals, 19(5), 503-511. doi: 10.1007/s10534-005-5449-0.

  9. Ge R.G., Watt R.M., Sun X., Tanner J.A., He Q.Y., Huang J.D.*, Sun H.Z.* (2006) “Expression and characterization of a histidine-rich protein: potential for Ni2+ storage in Helicobacter pylori” Biochemical Journal 393(Pt 1), 285-293. doi: 10.1042/BJ20051160.

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2005

  1. Chai Y., Yan S.C., Wong I.L.K., Chow L.M.C., Sun H.Z.* (2005) “Complexation of antimony (SbV) with 5´-GMP and 5´-GDP-mannose: formation of both mono- and bis-adducts” Journal of Inorganic Biochemistry, 99(12), 2257-2263. doi: 10.1016/j.jinorgbio.2005.08.015.

  2. Zheng B.J., Guan Y., He M.L., Sun H.Z., Du L., Zheng Y., Wong K.L., Chen H., Chen Y., Lu L., Tanner J.A., Watt R.M., Niccolai N., Bernini A., Spiga O., Woo P.C., Kung H.F., Yuen K.Y., Huang J.D. (2005) “Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus” Antiviral Therapy, 10(3), 393-403.

  3. Chen R., So M.H., Che C.-M., Sun H.Z.* (2005) “Controlled synthesis of high crystalline bismuth sulfide nanorods: using bismuth citrate as a precursor” Journal of Materials Chemistry, 15(42), 4540-4545. doi: 10.1039/B510299E.

  4. Yang P.Y., Gao H.Y., Cai J.Y., Chiu J.F., Sun H.Z., He Q.-Y. (2005) “The stepwise process of chromium-induced DNA breakage: characterization by electrochemistry, atomic force microscopy and DNA electrophoresis” Chemical Research in Toxicology, 18(10), 1563-1566. doi: 10.1021/tx050134w.

  5. Li H.Y., Li F., Kwan M.F., He Q.-Y., Sun H.Z.* (2005) “NMR structures and orientation of the fourth transmembrane domain of the rat divalent metal transporter (DMT1) with G185D mutation in SDS micelles” Biopolymers, 77(4), 173-183. doi: 10.1002/bip.20204.

  6. Li F., Li H.Y., Kwan M.F., Hu L.H., Chen G.H., He Q.-Y., Sun H.Z.* (2005) “Structure, assembly and topology of G185R mutant of the transmembrane domain4 of divalent metal transporter” Journal of the American Chemical Society, 127(5), 1414-1423. doi: 10.1021/ja047148t.

  7. Yan S.C., Jin L., Sun H.Z.* (2005) “51Sb- antimony in medicine” in ‘Metallotherapeutics Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine’ (eds. Tiekink E.R.T., Gielen M.), John Wiley & Sons, 441-461. doi: 10.1002/0470864052.ch23.

  8. Yang P.Y., Sun X. S., Chiu J.F., Sun H.Z., He Q.Y.* (2005) “Transferrin-mediated gold nanoparticle cellular uptake”. Bioconjugate Chemistry, 16(3), 494-496. doi: 10.1021/bc049775d. (Most-cited Article in 2005 in Bioconjugate Chemistry)

  9. Teng X.C., Zheng Q., Cai B., Ni F.Y., Xie Y., Sun H.Z., Zhang M.J., Huang Z.X. (2005) "An Insight of S-Nitrosylation of Human GIF" Chinese Journal of Chemistry, 23(11), 1545-1551. doi: 10.1002/cjoc.200591545.

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Department of Chemistry, The University of Hong Kong

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