Our research interest lies in Biological Inorganic Chemistry, in particular, metal in biology and medicine including design, synthesis of metalloagents as antimicrobials (or resistance breakers), and antivirals. Our particular interest is on bismuth drugs from mechanistic study to medicinal application. To understand the mechanism of action of metalloagents, we have established metalloproteomic approaches e.g. GE-ICP-MS/LC-GE-ICP-MS, fluorescence based approach, together with proteomics, metabolomics and transcriptomics, providing a platform for understanding the role of metals in biology and medicine at a system level. We are also interested in the structure and function of metalloproteins, in particular those that may serve as potential targets of metallodrugs.